Product Name: Semax CAS Number: 80714-61-0 Molecular Formula: C₃₇H₅₁N₉O₁₀S Amino Acid Sequence: H-Met-Glu-His-Phe-Pro-Gly-Pro-OH (Met-Glu-His-Phe-Pro-Gly-Pro) Purity: ≥98% (HPLC verified, some suppliers offer ≥99% purity grades) Formulation: Lyophilized powder (typically available in 5mg, 10mg, or custom vials)
🔬 Key Characteristics
Semax is a synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH), specifically the ACTH (4-10) sequence with a methionine extension. It exhibits high blood-brain barrier permeability and acts as a multifunctional neuroregulator, combining cognitive-enhancing, neuroprotective, and mood-stabilizing properties in preclinical research.
⚙️ Mechanism of Action
Neurotransmitter Modulation: Regulates monoamine neurotransmitters (dopamine, norepinephrine, serotonin) to enhance synaptic plasticity and cognitive function, while supporting mood balance through GABAergic system interactions.
Neurotrophic Activation: Stimulates transcription of neurotrophic factors (e.g., BDNF), promoting neuronal survival, dendrite growth, and repair mechanisms in models of brain injury or neurodegeneration.
Anti-Inflammatory Effects: Mitigates neuroinflammation by inhibiting pro-inflammatory cytokine release, contributing to its neuroprotective profile in ischemic or traumatic brain injury models.
📊 Research Applications
Cognitive Neuroscience: Studies on memory enhancement, attention span, and learning capacity in aging or cognitive impairment models.
Neuroprotection: Investigation of therapeutic potential in stroke, traumatic brain injury, and neurodegenerative disease research (e.g., Alzheimer’s, Parkinson’s).
Psychopharmacology: Evaluation of anxiolytic and mood-regulating effects in stress and anxiety disorder models.
💡 Product Features
Stability: Lyophilized form ensures long-term stability under recommended storage conditions (-20°C to -80°C, protected from light).
Reconstitution: Requires sterile solvent (e.g., bacteriostatic water) for laboratory use; exhibits good solubility in aqueous solutions.
Purity: High-grade formulation with ≥98% HPLC purity, suitable for in vitro and preclinical research applications.
⚠️ Disclaimer
For Research Use Only: Not approved for human or veterinary clinical applications. Handling requires adherence to standard peptide research protocols, including proper PPE and biosafety measures.
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This product contains Semaglutide in lyophilized (freeze-dried) powder form, requiring reconstitution before use.
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This product has multiple variants. The options may be chosen on the product page
